Patients need sustained wound healing^1,2

Rowan, a real patient with severe DEB

For this ultra-rare disease, sustained wound healing must become more common²

Severe dystrophic epidermolysis bullosa (DEB) is characterized by large, chronically open wounds that are associated with increased pruritus, pain, and complications including increased incidence of infection, and a high risk of aggressive squamous cell carcinoma.^3,4

Advancement in clinical research is helping us see the possibilities.¹

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References: 1. Keith AR, Twaroski K, Ebens CL, Tolar J. Leading edge: emerging drug, cell, and gene therapies for junctional epidermolysis bullosa. Expert Opin Biol Ther. 2020;20(8):911-923. doi:10.1080/14712598.2020.1740678. 2. Feinstein JA, Bruckner AL, Chastek B, Anderson A, Roman J. Clinical characteristics, healthcare use, and annual costs among patients with dystrophic epidermolysis bullosa. Orphanet J Rare Dis. 2022;17(1):367. doi:10.1186/s13023-022-02509-0. 3. Huitema L, Phillips T, Alexeev V, Igoucheva O. Immunological mechanisms underlying progression of chronic wounds in recessive dystrophic epidermolysis bullosa. Exp Dermatol. 2021;30(12):1724-1733. doi:10.1111/exd.14411. 4. Mellerio JE, Kiritsi D, Marinkovich MP, et al. Mapping the burden of severe forms of epidermolysis bullosa: implications for patient management. JAAD Int. 2023;11:224-232. doi:10.1016/j.jdin.2023.02.016.

Patients need sustained wound healing1,2

For this ultra-rare disease, sustained wound healing must become more common2

Sign up to stay informed on advances in severe DEB

Patients need sustained wound healing^1,2

For this ultra-rare disease, sustained wound healing must become more common²